
When Hollywood legend Harrison Ford canceled his appearance as a presenter at the 2025 Oscars due to a shingles diagnosis, it brought this often-misunderstood condition into the spotlight. While many associate shingles with older adults, the reality is that it can affect individuals of various ages, leading to significant discomfort and complications. Here’s what you need to know about shingles, its causes, symptoms, treatment options, and prevention strategies.
What Is Shingles?
Shingles, medically known as herpes zoster, is a viral infection resulting from the reactivation of the varicella-zoster virus—the same virus responsible for chickenpox. After an individual recovers from chickenpox, the virus remains dormant in the nerve tissue near the spinal cord and brain. Years or even decades later, the virus can reactivate, leading to shingles.
Causes and Risk Factors
The exact cause of the virus’s reactivation isn’t entirely understood, but, according to the Mayo Clinic, several factors can increase the risk:
- Age: Individuals over 50 are at a higher risk, with the likelihood increasing with age.
- Weakened Immune System: Conditions such as HIV/AIDS, cancer, or treatments like chemotherapy can compromise immunity.
- Stress: High levels of stress can weaken the immune system, potentially triggering reactivation.
- History of Chickenpox: Anyone who has had chickenpox is at risk for developing shingles later in life.
Symptoms to Watch For
Shingles typically affects a small section on one side of the body. Early signs and symptoms may include:
- Pain, Burning, or Tingling: Often the first symptom, this discomfort usually precedes the rash by a few days.
- Red Rash: Develops a few days after the pain, typically appearing as a stripe of blisters that wraps around either the left or right side of the torso. It can also occur around one eye or on one side of the neck or face.
- Fluid-Filled Blisters: These break open and crust over within 7 to 10 days and heal completely in two to four weeks.
- Other Symptoms: Fever, headache, sensitivity to light, and fatigue.
Potential Complications
While shingles isn’t usually life-threatening, it can lead to serious complications:
- Postherpetic Neuralgia (PHN): Characterized by severe nerve pain that persists after the rash has healed. According to Glamour, approximately 10-18% of individuals with shingles experience PHN, which can last for months or even years.
- Vision Loss: If shingles occurs in or around the eye (herpes zoster ophthalmicus), it can cause painful eye infections and potentially lead to vision loss.
- Neurological Problems: Depending on which nerves are affected, shingles can cause inflammation of the brain (encephalitis), facial paralysis, or hearing or balance problems.
- Skin Infections: If the blisters aren’t properly cared for, bacterial skin infections may develop.
Treatment Options
While there’s no cure for shingles, early treatment can help shorten the duration of the infection and reduce the risk of complications:
- Antiviral Medications: Drugs like acyclovir, valacyclovir, or famciclovir can speed healing and lessen the severity of the illness if started within 72 hours of the first symptoms.
- Pain Relievers: Over-the-counter pain medications or prescription drugs can help manage discomfort.
- Topical Treatments: Applying calamine lotion or using wet compresses can soothe irritated skin.
For those suffering from PHN, treatment options may include:
- Nerve Pain Medications: Drugs such as gabapentin or pregabalin can help alleviate nerve pain.
- Nerve Blocks: Injections that can provide temporary relief by blocking pain signals.
- Spinal Cord Stimulation: A treatment option for long-term pain relief when other therapies have failed.
Prevention Strategies
Vaccination is the most effective way to reduce the risk of developing shingles and its complications:
- Shingrix Vaccine: Recommended for adults over 50 and immunocompromised individuals starting at age 19, Shingrix provides about 90% protection against shingles and PHN. It’s administered in two doses, with the second dose given two to six months after the first.
Harrison Ford’s recent battle with shingles serves as a reminder that this condition doesn’t discriminate, underscoring the importance of awareness and proactive healthcare decisions.